I waited to go until friends came to visit, since I guessed that anyone visiting would probably want to go and I was pretty sure I would want to go twice (I was right). It's only 1 block from where I live, and during the day there is a long line outside. Come back at 7 PM and there's no line. The museum is open until 8:30 in the late-spring/summer/early-fall.
The huge lines aren't so bad because they're fast moving. That's because there's nothing to see inside. They don't take Museum Cards, but it's only f10. However, f10 is a lot to pay to see any empty house. During the war, the Germans took everything out of the house. Anne Frank's father wanted it preserved that way, and thus it has remained a mostly empty house.
When you enter, you see a model of the house, furnished as it would have been when the Frank's were hiding here. Take a good look, since the house itself is empty. You also get to see 3 videos (about 10 minutes total), the bookcase door, and pictures that Anne pasted on the wall. You literally are paying to see the house and little more.
At the end, they have a high-tech pseudo-intellectual display discussing related issues relevant to today's society, with high-minded sounding (and somethings incoherent) quotes from eminent authorities that you've never heard of.
Sound cynical? Definitely. I was told there wasn't much in the house and that it was depressing. I went in with low expectations. My expectations were crushed, and the depressing part was paying f10 to see an empty house. My opinion is your better off buying a copy of Anne Frank's diary and reading it rather than seeing the house. However, your milage may vary, and the intent of the high-tech display at the end is good (I just feel they didn't pull it off). They were renovating when I went there, so perhaps they put something else in.



